Nursing jobs in South Dakota
130 open nursing jobs in South Dakota: 58 RN, 37 LPN/LVN, 23 CNA, 9 NP, 3 Travel. Apply directly with the employer. Includes 7 federal postings that also cover other states.
130 jobs
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Addiction Care CenterAvera HealthSioux Falls, SD$24.50–$48.50/hrLPN/LVNPsychFull-timeNightsDaysSign-on bonus
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | OBGYN Marion RoadAvera HealthSioux Falls, SD$22.50–$41.25/hrLPN/LVNFull-timeDays
- LPN - Licensed Practical Nurse - Allergy Clinic - FT DaysSanford HealthSioux Falls, SD$21.75–$29.50/hrLPN/LVNFull-timeDaysSign-on bonus
- LPN Float - Licensed Practical Nurse - Clinic Float Pool - FT DaysSanford HealthSioux Falls, SD$21.75–$29.50/hrLPN/LVNPer diem / PRNDaysSign-on bonus
- Nursing Assistant- Specialty CareVeterans Health AdministrationSioux Falls, SD$40k–$59k/yrCNAFull-timeCloses Feb 4, 2027
- Advanced Practice Nurse (Midwife)Indian Health ServiceKyle, SD$117k–$164k/yrNPFull-timeSign-on bonusCloses Dec 4, 2026
- Advanced Practice Nurse (Nurse Practitioner) - Primary Care - EDRP EligibleVeterans Health AdministrationHot Springs, SD$111k–$174k/yrNPFull-timeCloses Nov 16, 2026
- Nurse (QAPI)Indian Health ServiceLower Brule, SD$98k–$128k/yrRNFull-timeCloses Dec 31, 2026
- Nurse (Registered Nurse) Recruitment Incentive - Direct HireBureau of Prisons/Federal Prison SystemMultiple locations (105)$50k–$122k/yrRNFull-timeCloses Sep 30, 2027
- Registered Nurse - RNFresenius Medical CareDakota Dunes, SDRNDialysisFull-time
- LPN - Licensed Practical Nurse or MA - Medical Assistant - 34th & Kiwanis Family Medicine Clinic - FT DaysSanford HealthSioux Falls, SD$19–$29.50/hrLPN/LVNFull-timeDaysSign-on bonus
- Nursing Assistant Trainee - FT - DaysSanford HealthMiller, SD$15–$23/hrCNAFull-timeDays
- Registered Nurse (RN) Visit Nurse | Home Health and HospiceAvera HealthAberdeen, SD$31–$46.25/hrRNFull-timeNightsSign-on bonus
- Registered Nurse (RN) | PACUAvera HealthMitchell, SD$32.50–$48.50/hrRNORFull-timeNightsSign-on bonus
- Nursing Assistant- Inpatient Specialty CareVeterans Health AdministrationSioux Falls, SD$40k–$59k/yrCNAMed-surgFull-timeCloses Nov 13, 2026
- Nurse (Peds)Indian Health ServicePine Ridge, SD$73k–$110k/yrRNPediatricsFull-timeCloses Nov 6, 2026
- Licensed Practical NurseIndian Health ServiceMultiple locations (14)$47k–$74k/yrLPN/LVNFlexible / otherSign-on bonusCloses Dec 31, 2026
- Registered Nurse - Community Living CenterVeterans Health AdministrationSioux Falls, SD$66k–$120k/yrRNFull-timeCloses Dec 2, 2026
- RN Outpatient - Stacy BarnesSanford HealthRapid City, SD$32–$48/hrRNFull-timeDays
- Registered Nurse (Clinic RN)|Licensed Practical Nurse (LPN)|Gregory ClinicAvera HealthGregory, SD$22.50–$41.25/hrLPN/LVNFull-timeDays
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Urgent CareAvera HealthSioux Falls, SD$22.50–$41.25/hrLPN/LVNPart-time
- RN - Registered Nurse - RCC - PRN NightsSanford HealthRapid City, SD$34–$48/hrRNPer diem / PRNNights
- Nurse (Specialty Departments)Indian Health ServiceMultiple locations (21)$84k–$128k/yrRNFlexible / otherSign-on bonusCloses Dec 31, 2026
- Nurse (Outpatient)Indian Health ServiceMultiple locations (114)$73k–$110k/yrRNFlexible / otherSign-on bonusCloses Dec 31, 2026
- Advanced Practice Nurse - CardiologyVeterans Health AdministrationSioux Falls, SD$95k–$149k/yrNPCardiacFull-timeCloses Dec 2, 2026
- RN - Registered Nurse - RCC - PRNSanford HealthRapid City, SD$34–$48/hrRNPer diem / PRNDays
- RN - Registered Nurse - Ava's Hospice House - WeekendsSanford HealthSioux Falls, SD$32–$48/hrRNFull-timeWeekends
- Certified Nursing Assistant (CNA)|Gregory Nursing HomeAvera HealthGregory, SD$19.75–$26/hrCNAFull-timeNightsDays
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term CareAvera HealthAberdeen, SD$24.50–$48.50/hrLPN/LVNFull-time
- Advanced Practice Nurse (Psychiatric)Indian Health ServiceMultiple locations (98)$111k–$164k/yrNPPsychFlexible / otherSign-on bonusCloses Dec 31, 2026
- Certified Nurse MidwifeIndian Health ServiceMultiple locations (8)$111k–$164k/yrRNFlexible / otherSign-on bonusCloses Dec 31, 2026
- RN - Aberdeen Emergency Department - Part Time - every third weekendSanford HealthAberdeen, SD$33.50–$48/hrRNERPart-timeWeekends
- LPN or MA - Family MedicineSanford HealthRapid City, SD$20–$29.50/hrLPN/LVNFull-timeDays
- Certified Nursing Assistant II (CNA)Avera HealthSouth Dakota$20.75–$27.50/hrCNAPart-time
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Medical Oncology ClinicAvera HealthSioux Falls, SD$22.50–$41.25/hrLPN/LVNOncologyPart-timeDays$20,000 sign-on bonus
- Advanced Practice Nurse (Nurse Practitioner)Indian Health ServiceMultiple locations (102)$111k–$164k/yrNPFlexible / otherSign-on bonusCloses Dec 31, 2026
- RN - Registered Nurse - Acute DialysisSanford HealthSioux Falls, SD$32–$48/hrRNDialysisFull-timeDaysSign-on bonus
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term CareAvera HealthYankton, SD$24.50–$48.50/hrLPN/LVNPart-timeDaysSign-on bonus
- Registered Nurse (RN), Licensed Practical Nurse (LPN) | Clinic FloatAvera HealthAberdeen, SD$22.50–$41.25/hrLPN/LVNFull-timeDaysSign-on bonus
- Travel - Interim Director of Nursing - RN - Long Term CareSanford HealthCity, SDTravelContractDays
- Nurse Educator - Maternal HealthAvera HealthSioux Falls, SD$34.50–$51.50/hrRNL&DFull-timeDays
- Nursing Assistant or Certified Nursing Assistant (CNA) II | Long Term CareAvera HealthParkston, SD$19.75–$27.50/hrCNAFull-timeNightsDaysSign-on bonus
- Director of Nursing - RN - Long Term CareSanford HealthTyndall, SDRNFull-timeDays$25,000 sign-on bonus
- Nursing Assistant Trainee - PTSanford HealthDe Smet, SDCNAPart-time
- Registered Nurse (RN), Licensed Practical Nurse (LPN), Medical Assistant (MA) | ClinicAvera HealthMiller, SD$20–$41.25/hrLPN/LVNFull-timeEvenings
- Registered Nurse (RN) | OR | SurgeryAvera HealthSioux Falls, SD$31–$46.25/hrRNORFull-timeDays
- RN Inpatient - Med Surg/EDSanford HealthAberdeen, SDRNERFull-time
- RN Traveler - EDSanford HealthChamberlain, SDTravelERContract
- Registered Nurse (RN) | SurgeryAvera HealthSioux Falls, SD$32.50–$48.50/hrRNFull-timeEvenings
- Registered Nurse (RN) - Visiting Nurse | Home Care MitchellAvera HealthMitchell, SD$31–$46.25/hrRNFull-timeNightsSign-on bonus
- RN Traveler - Med Surg/OBSanford HealthChamberlain, SDTravelL&DContract
- APP - Physician Assistant or Nurse Practitioner | HospitalistSanford HealthRapid City, SDNPFull-timeNightsDays
- Nursing Assistant or Certified Nursing Assistant (CNA) | Long Term CareAvera HealthYankton, SD$19.75–$27.50/hrCNAFull-timeSign-on bonus
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term CareAvera HealthParkston, SD$24.50–$48.50/hrLPN/LVNFull-timeNightsDays$10,000 sign-on bonus
- Certified Nursing Assistant (CNA) or Nurse Assistant | Hospice HouseAvera HealthYankton, SD$19.75–$27.50/hrCNAPart-time
- Registered Nurse (RN) or Licensed Practical Nurse (LPN) | ClinicAvera HealthSioux Falls, SD$22.50–$41.25/hrLPN/LVNFull-timeDaysSign-on bonus
- Nursing Assistant or Certified Nursing Assistant (CNA) | Long Term Care | PRNAvera HealthParkston, SD$19.75–$26/hrCNAPer diem / PRNNightsDays
- Certified Nursing Assistant (CNA) or Nurse Assistant FLOAT | Long Term CareAvera HealthYankton, SD$19.75–$27.50/hrCNAFull-timeNights
- Nursing Assistant or Certified Nursing Assistant (CNA) | Long Term CareAvera HealthParkston, SD$19.75–$26/hrCNAPart-timeNightsDays
- Registered Nurse (RN) | NICUAvera HealthSioux Falls, SD$32.50–$48.50/hrRNNICUFull-timeNightsDays$15,000 sign-on bonus
Cities in South Dakota
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Nurse pay in South Dakota
| Role | Median hourly | Median yearly |
|---|---|---|
| Registered Nurse | $33.42/hr | $69,510/yr |
| Licensed Practical Nurse | $23.64/hr | $49,170/yr |
| Certified Nursing Assistant | $18.30/hr | $38,070/yr |
| Nurse Practitioner | $58.94/hr | $122,600/yr |
Source: U.S. Bureau of Labor Statistics, OEWS May 2024 state estimates.
Remote and telehealth nursing jobs
Check each listing’s licence requirement; many need a licence valid in the patient’s state.
- Registered Nurse – Physician PracticeSentara HealthRemote$38.01–$55.42/hrRNFull-timeDaysWeekends
- UTILIZATION REVIEW NURSESentara HealthRemote$93k–$137k/yrRNFull-timeDays
- Nurse Practitioner, Results Review (Remote - Contractor, 3-months)PrenuvoRemote$60–$65/hrNPContract
- Telehealth Psychiatric Nurse Practitioner - Eating Disorders (EST - Remote)EquipRemote$120k–$150k/yrNPPsychFull-time
- Telehealth Family Nurse Practitioner - Eating Disorders (EST-Remote)EquipRemote$110k–$150k/yrNPFull-time
- Remote Triage NurseFirsthand HealthRemote$80k–$80k/yrRNFlexible / other